Botulinum (Botox®)

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The botulinum (Botox®) is anincreasingly applied drug in the aesthetic medicine. It consists of purified botulinum toxin of type A. Its injection blocks the transmissions of nervous impulses on the neuromuscular junction. The botulinum was applied for the first time in ophthalmology in 1977 for the treatment of strabismus. In the early 90's, its application was extended to aesthetic treatments,initially to treat muscular spasms and dystonia. The botulinum toxin is a substance produced by the bacterium Clostridium Botulinum. Its injection into the muscles blocks the release of acetylcholine at the neuromuscular junction and consequently also the stimulation of muscle contractions. There for, if Botox® is injected into facial muscles, it decreases their contracting activity, reducing this way the face wrinkles caused by the contraction of such muscles.

The botulinum is applied to reduce the wrinkles on the forehead, between the eyebrows, and around the eyes (see also "Reduction of wrinkles with Botox®). In addition, this drug is widely used for the treatment of hyperhidrosis (excessive sweating) in various areas of the body, but especially in the armpits (see also "Treatment of excessive sweating with Botox®).  

Although it has already been used for many years, it should be noted that botulinum is a drug that should only be applied by experienced doctors and specialized clinics. Botulinum treatments must not be performed by inexperienced persons and it is prohibited to apply self - injections because damages can be significant. The Botox®, which has already been widely experimented and applied for many years in ophthalmology and aesthetic medicine, does not cause any particular complications. The allergic reactions are very rare – it is a safe medicament for aesthetic treatments when applied by experienced specialists. In rare cases, side effects may include headaches, dizziness, sagging of the lower eyelids, weakness of the treated muscles and lachrymation in cases of applications around the eyes. However, these side effects are temporary. It should be noted that the immune system can react by producing antibodies that recognize and neutralize the botulinum toxin, thus eliminating its effect. Botulinum treatments are not recommended for pregnant women or people with neuromuscular problems.


Due to its safety and guarantee in aesthetic treatments application, botulinum is nowadays one of the most applied products in Europe and the United States. The facial treatment with botulinum can be performed at any age, in cases of a real medical - aesthetic indication. KEIT® REFUSES TO PERFORM BOTULINUM AESTHETIC TREATMENTS ON MINORS in full compliance withthe highest standards of professional ethics and in full respect of all people’s health. KEIT® prefers to apply high quality botulinum of the American (Vistabex, Allergan®, and German (Bocuture, Merz Pharma Group, international brands.